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- Researchers investigated how common preservatives sodium benzoate and phenoxyethanol disrupt bacteria through integrated imaging and biochemical analysis.
- The study found that these chemicals attack bacteria by compromising cell envelopes and causing internal damage to proteins and genetic material.
- Sodium benzoate causes cellular shrinkage, while phenoxyethanol leads to membrane expansion and rupture.
- These insights will assist manufacturers in selecting more effective preservatives for different product types.
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Department of Science and Technology
1 quote · 1 outlet
“Rather than a single mode of action, the preservatives deliver a coordinated multi-target assault, providing one of the clearest views yet of how bacterial cells are inactivated”
In the article
…physically compromised, while reactive aldehydes and oxygen-derived species accumulate inside the cell, disrupting essential proteins, genetic material and other critical cellular functions. Multi-target assault “ Rather than a single mode of action, the preservatives deliver a coordinated multi-target assault, providing one of the clearest views yet of how bacterial cells are inactivated ,” the department said. It added that advanced imaging revealed that sodium benzoate and phenoxyethanol follow distinct pathways to bacterial inactivation. Sodium benzoate induced cellular shrinkage and collapse,…
Coverage1
All filed from India
Named India · Department of Science and Technology · Institute of Nano Science and Technology · Unilever R&D
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