The record
Written from the 1 report below. Nothing here is unsourced.
- Moderna and Merck reported promising results from a clinical trial of a personalised skin cancer vaccine, Intismeran, given alongside the immunotherapy drug Keytruda.
- The vaccine was given to high-risk melanoma patients after surgery, and was built using mRNA technology, the same used in some Covid-19 vaccines.
- Companies said patients who received the vaccine with Keytruda stayed cancer-free for a significantly longer period than patients on Keytruda alone, and the risk of the disease spreading to other organs also fell.
- The vaccine is customised for each patient by sequencing DNA from a sample of the patient's tumour so the immune system can target the exact mutations in the cancer cells.
- Experts welcomed the findings as a potential turning point in cancer treatment but urged caution, since full trial results, independent review and regulator approval are still pending before the vaccine can be used in routine care.
What to watch next
- Publication of full, final trial results and independent expert review of the findings
- Regulatory approval decisions for the vaccine
- Progress of ongoing trials of similar personalised vaccines for lung, bladder and kidney cancers
Who said what1
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Stéphane Bancel
1 quote · 1 outlet
“हे संशोधन कॅन्सर उपचारांच्या इतिहासातील एक ऐतिहासिक वळण आहे”
In the article
…पेशी शोधून काढून त्या पूर्णपणे नष्ट करण्याचा स्पष्ट संदेश देते. फुफ्फुस, मूत्राशय तसेच किडनीच्या कॅन्सरवर मात करण्यासाठीही या दोन्ही औषध कंपन्यांकडून अशाच स्वरूपाच्या पर्सनलाइज्ड लसींच्या वैद्यकीय चाचण्या सुरू आहेत. " हे संशोधन कॅन्सर उपचारांच्या इतिहासातील एक ऐतिहासिक वळण आहे ," असा विश्वास मॉडर्नाचे मुख्य कार्यकारी अधिकारी स्टेफेन बँसेल यांनी व्यक्त केला. या मोठ्या घोषणेचा सकारात्मक परिणाम शेअर बाजारावरही दिसला असून, मॉडर्ना आणि मर्क या दोन्ही कंपन्यांच्या शेअर्समध्ये जोरदार उसळी नोंदवली…
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Named United Kingdom · United States · Cancer Research UK · Keytruda · Lennard Lee · Merck · Moderna · Stéphane Bancel · Talicia Quallo · University of Oxford
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