The record
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- An ICMR nationwide surveillance study of 6,889 dengue samples from 25 States and Union Territories found multiple dengue virus serotypes circulating simultaneously across much of India, with DENV-2 the most common.
- All four serotypes were reported in eight States and Union Territories, and about 7% of patients carried more than one serotype at the same time.
- Patients with concurrent infections were more likely to show severe symptoms such as low platelet counts, bleeding and severe joint pain.
- The findings matter because vaccine effectiveness varies by strain, complicating plans to introduce dengue vaccines into public health programmes.
What to watch next
- Confirmation of the link between multi-serotype infections and severe disease through long-term clinical studies
- Progress of indigenous dengue vaccine candidates and rollout plans for the recently cleared imported vaccine
- Shifts in the dominant serotype revealed by ongoing surveillance, which could affect outbreak intensity and vaccine performance
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Named India · Ashoka University · Gautam Menon · Indian Council of Medical Research · Virus Research and Diagnostic Laboratory
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